The role of high-field magnetic resonance imaging in parkinsonian disorders: Pushing the boundaries forward.
Identifieur interne : 000006 ( Main/Exploration ); précédent : 000005; suivant : 000007The role of high-field magnetic resonance imaging in parkinsonian disorders: Pushing the boundaries forward.
Auteurs : Stéphane Lehericy [France] ; David E. Vaillancourt [États-Unis] ; Klaus Seppi [Autriche] ; Oury Monchi [Canada] ; Irena Rektorova [République tchèque] ; Angelo Antonini [Italie] ; Martin J. Mckeown [Canada] ; Mario Masellis [Canada] ; Daniela Berg [Allemagne] ; James B. Rowe [Royaume-Uni] ; Simon J G. Lewis [Australie] ; Caroline H. Williams-Gray [Royaume-Uni] ; Alessandro Tessitore [Italie] ; Hartwig R. Siebner [Danemark]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2017.
Abstract
Historically, magnetic resonance imaging (MRI) has contributed little to the study of Parkinson's disease (PD), but modern MRI approaches have unveiled several complementary markers that are useful for research and clinical applications. Iron- and neuromelanin-sensitive MRI detect qualitative changes in the substantia nigra. Quantitative MRI markers can be derived from diffusion weighted and iron-sensitive imaging or volumetry. Functional brain alterations at rest or during task performance have been captured with functional and arterial spin labeling perfusion MRI. These markers are useful for the diagnosis of PD and atypical parkinsonism, to track disease progression from the premotor stages of these diseases and to better understand the neurobiological basis of clinical deficits. A current research goal using MRI is to generate time-dependent models of the evolution of PD biomarkers that can help understand neurodegeneration and provide reliable markers for therapeutic trials. This article reviews recent advances in MRI biomarker research at high-field (3T) and ultra high field-imaging (7T) in PD and atypical parkinsonism. © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.
DOI: 10.1002/mds.26968
PubMed: 28370449
Affiliations:
- Allemagne, Australie, Autriche, Canada, Danemark, France, Italie, Royaume-Uni, République tchèque, États-Unis
- Alberta, Angleterre, Angleterre de l'Est, Bade-Wurtemberg, District de Tübingen, Floride, Moravie, Ontario, Île-de-France
- Brno, Calgary, Cambridge, Paris, Sydney, Toronto, Tübingen
- Université de Calgary, Université de Cambridge, Université de Toronto
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Vaillancourt</name><affiliation wicri:level="2"><nlm:affiliation>Department of Applied Physiology and Kinesiology, Department of Neurology and Centre for Movement Disorders and Neurorestoration, Department of Biomedical Engineering, University of Florida, Gainesville, Florida, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Applied Physiology and Kinesiology, Department of Neurology and Centre for Movement Disorders and Neurorestoration, Department of Biomedical Engineering, University of Florida, Gainesville, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical University Innsbruck, Innsbruck, Austria and Neuroimaging Research Core Facility, Medical University Innsbruck, Innsbruck, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck, Austria and Neuroimaging Research Core Facility, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Monchi, Oury" sort="Monchi, Oury" uniqKey="Monchi O" first="Oury" last="Monchi">Oury Monchi</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Neurosciences, Department of Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Neurosciences, Department of Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Rektorova, Irena" sort="Rektorova, Irena" uniqKey="Rektorova I" first="Irena" last="Rektorova">Irena Rektorova</name><affiliation wicri:level="3"><nlm:affiliation>First Department of Neurology, School of Medicine, St. Anne's University Hospital, Brain and Mind Research Program, Central European Institute of Technology, Masaryk University, Brno, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>First Department of Neurology, School of Medicine, St. Anne's University Hospital, Brain and Mind Research Program, Central European Institute of Technology, Masaryk University, Brno</wicri:regionArea><placeName><settlement type="city">Brno</settlement><region>Moravie</region></placeName></affiliation></author><author><name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name><affiliation wicri:level="1"><nlm:affiliation>Parkinson and Movement Disorders Unit, istituto di ricovero e cura a carattere scientifico (IRCCS) Hospital San Camillo, Venice and Department of Neurosciences (DNS), Padova University, Padova, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Parkinson and Movement Disorders Unit, istituto di ricovero e cura a carattere scientifico (IRCCS) Hospital San Camillo, Venice and Department of Neurosciences (DNS), Padova University, Padova</wicri:regionArea><wicri:noRegion>Padova</wicri:noRegion></affiliation></author><author><name sortKey="Mckeown, Martin J" sort="Mckeown, Martin J" uniqKey="Mckeown M" first="Martin J" last="Mckeown">Martin J. Mckeown</name><affiliation wicri:level="1"><nlm:affiliation>Pacific Parkinson's Research Center, Department of Medicine (Neurology), University of British Columbia Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Pacific Parkinson's Research Center, Department of Medicine (Neurology), University of British Columbia Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Masellis, Mario" sort="Masellis, Mario" uniqKey="Masellis M" first="Mario" last="Masellis">Mario Masellis</name><affiliation wicri:level="4"><nlm:affiliation>Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Christian-Albrechts-University of Kiel and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Christian-Albrechts-University of Kiel and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Rowe, James B" sort="Rowe, James B" uniqKey="Rowe J" first="James B" last="Rowe">James B. Rowe</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Neurosciences, Cambridge University, and Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Cambridge University, and Medical Research Council Cognition and Brain Sciences Unit, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Lewis, Simon J G" sort="Lewis, Simon J G" uniqKey="Lewis S" first="Simon J G" last="Lewis">Simon J G. Lewis</name><affiliation wicri:level="3"><nlm:affiliation>Parkinson's Disease Research Clinic, Brain and Mind Centre, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Parkinson's Disease Research Clinic, Brain and Mind Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Williams Gray, Caroline H" sort="Williams Gray, Caroline H" uniqKey="Williams Gray C" first="Caroline H" last="Williams-Gray">Caroline H. Williams-Gray</name><affiliation wicri:level="4"><nlm:affiliation>John Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>John Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Tessitore, Alessandro" sort="Tessitore, Alessandro" uniqKey="Tessitore A" first="Alessandro" last="Tessitore">Alessandro Tessitore</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, Second University of Naples, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, Second University of Naples, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Siebner, Hartwig R" sort="Siebner, Hartwig R" uniqKey="Siebner H" first="Hartwig R" last="Siebner">Hartwig R. Siebner</name><affiliation wicri:level="1"><nlm:affiliation>Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Department of Neurology, Copenhagen University Hospital Bispebjerg, Hvidovre, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Department of Neurology, Copenhagen University Hospital Bispebjerg, Hvidovre</wicri:regionArea><wicri:noRegion>Hvidovre</wicri:noRegion></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Historically, magnetic resonance imaging (MRI) has contributed little to the study of Parkinson's disease (PD), but modern MRI approaches have unveiled several complementary markers that are useful for research and clinical applications. Iron- and neuromelanin-sensitive MRI detect qualitative changes in the substantia nigra. Quantitative MRI markers can be derived from diffusion weighted and iron-sensitive imaging or volumetry. Functional brain alterations at rest or during task performance have been captured with functional and arterial spin labeling perfusion MRI. These markers are useful for the diagnosis of PD and atypical parkinsonism, to track disease progression from the premotor stages of these diseases and to better understand the neurobiological basis of clinical deficits. A current research goal using MRI is to generate time-dependent models of the evolution of PD biomarkers that can help understand neurodegeneration and provide reliable markers for therapeutic trials. This article reviews recent advances in MRI biomarker research at high-field (3T) and ultra high field-imaging (7T) in PD and atypical parkinsonism. © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Canada</li><li>Danemark</li><li>France</li><li>Italie</li><li>Royaume-Uni</li><li>République tchèque</li><li>États-Unis</li></country><region><li>Alberta</li><li>Angleterre</li><li>Angleterre de l'Est</li><li>Bade-Wurtemberg</li><li>District de Tübingen</li><li>Floride</li><li>Moravie</li><li>Ontario</li><li>Île-de-France</li></region><settlement><li>Brno</li><li>Calgary</li><li>Cambridge</li><li>Paris</li><li>Sydney</li><li>Toronto</li><li>Tübingen</li></settlement><orgName><li>Université de Calgary</li><li>Université de Cambridge</li><li>Université de Toronto</li></orgName></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Lehericy, Stephane" sort="Lehericy, Stephane" uniqKey="Lehericy S" first="Stéphane" last="Lehericy">Stéphane Lehericy</name></region></country><country name="États-Unis"><region name="Floride"><name sortKey="Vaillancourt, David E" sort="Vaillancourt, David E" uniqKey="Vaillancourt D" first="David E" last="Vaillancourt">David E. Vaillancourt</name></region></country><country name="Autriche"><noRegion><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name></noRegion></country><country name="Canada"><region name="Alberta"><name sortKey="Monchi, Oury" sort="Monchi, Oury" uniqKey="Monchi O" first="Oury" last="Monchi">Oury Monchi</name></region><name sortKey="Masellis, Mario" sort="Masellis, Mario" uniqKey="Masellis M" first="Mario" last="Masellis">Mario Masellis</name><name sortKey="Mckeown, Martin J" sort="Mckeown, Martin J" uniqKey="Mckeown M" first="Martin J" last="Mckeown">Martin J. Mckeown</name></country><country name="République tchèque"><region name="Moravie"><name sortKey="Rektorova, Irena" sort="Rektorova, Irena" uniqKey="Rektorova I" first="Irena" last="Rektorova">Irena Rektorova</name></region></country><country name="Italie"><noRegion><name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name></noRegion><name sortKey="Tessitore, Alessandro" sort="Tessitore, Alessandro" uniqKey="Tessitore A" first="Alessandro" last="Tessitore">Alessandro Tessitore</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name></region></country><country name="Royaume-Uni"><noRegion><name sortKey="Rowe, James B" sort="Rowe, James B" uniqKey="Rowe J" first="James B" last="Rowe">James B. Rowe</name></noRegion><name sortKey="Williams Gray, Caroline H" sort="Williams Gray, Caroline H" uniqKey="Williams Gray C" first="Caroline H" last="Williams-Gray">Caroline H. Williams-Gray</name></country><country name="Australie"><noRegion><name sortKey="Lewis, Simon J G" sort="Lewis, Simon J G" uniqKey="Lewis S" first="Simon J G" last="Lewis">Simon J G. Lewis</name></noRegion></country><country name="Danemark"><noRegion><name sortKey="Siebner, Hartwig R" sort="Siebner, Hartwig R" uniqKey="Siebner H" first="Hartwig R" last="Siebner">Hartwig R. Siebner</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000006 | SxmlIndent | more
Ou
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Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28370449
|texte= The role of high-field magnetic resonance imaging in parkinsonian disorders: Pushing the boundaries forward.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28370449" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |